DDI Publications List

Kochumon S, Arefanian H, Azim R, Shenouda S, Jacob T, Abu Khalaf N, Al-Rashed F, Hasan A, Sindhu S, Al-Mulla F, Ahmad R. Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway. Biomedicines. 2020 Oct 9;8(10):403. doi: 10.3390/biomedicines8100403. PMID: 33050324; PMCID: PMC7600458.

Hasan A, Kochumon S, Al-Ozairi E, Tuomilehto J, Al-Mulla F, Ahmad R. Correlation Profile of Suppression of Tumorigenicity 2 and/or Interleukin-33 with Biomarkers in the Adipose Tissue of Individuals with Different Metabolic States. Diabetes Metab Syndr Obes. 2020 Oct 20;13:3839-3859. doi: 10.2147/DMSO.S251978. PMID: 33116731; PMCID: PMC7586022.

Sina M, Ghorbanoghli Z, Abedrabbo A, Al-Mulla F, Sghaier RB, Buisine MP, Cortas G, Goshayeshi L, Hadjisavvas A, Hammoudeh W, Hamoudi W, Jabari C, Loizidou MA, Majidzadeh-A K, Marafie MJ, Muslumov G, Rifai L, Seir RA, Talaat SM, Tunca B, Ziada-Bouchaar H, Velthuizen ME, Sharara AI, Ahadova A, Georgiou D, Vasen HFA; Middle East Network on Hereditary Colorectal Cancer (HCCN-ME). Identification and management of Lynch syndrome in the Middle East and North African countries: outcome of a survey in 12 countries. Fam Cancer. 2020 Oct 24. doi: 10.1007/s10689-020-00211-3. Epub ahead of print. PMID: 33098072.

Alkandari A, Alarouj M, Elkum N, Sharma P, Devarajan S, Abu-Farha M, Al-Mulla F, Tuomilehto J, Bennakhi A. Adult Diabetes and Prediabetes Prevalence in Kuwait: Data from the Cross-Sectional Kuwait Diabetes Epidemiology Program. J Clin Med. 2020 Oct 25;9(11):E3420. doi: 10.3390/jcm9113420. PMID: 33113867.

Alahmad B, Al-Shammari AA, Bennakhi A, Al-Mulla F, Ali H. Fasting Blood Glucose and COVID-19 Severity: Nonlinearity Matters. Diabetes Care. 2020 October. Epub. https://doi.org/10.2337/dc20-1941

Al-Rashed F, Ahmad Z, Thomas R, Melhem M, Snider AJ, Obeid LM, Al-Mulla F, Hannun YA, Ahmad R. Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α. Sci Rep. 2020 Oct 8;10(1):16802. doi:10.1038/s41598-020-73912-5. PMID: 33033337.

Abu-Farha M, Ghosh A, Al-Khairi I, Madiraju SRM, Abubakr J, Prentki M. The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation. Prog Lipid Res. 2020 Oct 2;80:101067. doi: 10.1016/j.plipres.2020.101067. Epub ahead of print. PMID: 33011191

Kochumon S, Al Madhoun A, Al-Rashed F, Thomas R, Sindhu S, Al-Ozairi E, Al- Mulla F, Ahmad R. Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance. Sci Rep. 2020 Oct 1;10(1):16364. doi: 10.1038/s41598-020-73347-y. PMID: 33004937; PMCID: PMC7530670.

Zhang Q, Bastard P, Liu Z, ... Al-Mulla F, et al. Inborn errors of type I IFN immunity in patients with life-threaten ng COVID-19. Science. 2020 Oct 23;370(6515):eabd4570. doi: 10.1126/science.abd4570.

Hebbar P, Abubaker JA, Abu-Farha M, Alsmadi O, Elkum N, Alkayal F, John SE, Channanath A, Iqbal R, Pitkaniemi J, Tuomilehto J, Sladek R, Al-Mulla F, Thanaraj TA. Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population. Hum Genet. 2020 Sep 9. doi: 10.1007/s00439-020-02222-7. Epub ahead of print. PMID: 32902719.

Al Madhoun A, Marafie SK, Haddad D, Melhem M, Abu-Farha M, Ali H, Sindhu S, Atari M, Al-Mulla F. Comparative Proteomic Analysis Identifies EphA2 as a Specific Cell Surface Marker for Wharton's Jelly-Derived Mesenchymal Stem Cells. Int J Mol Sci. 2020 Sep 3;21(17):E6437. doi: 10.3390/ijms21176437. PMID: 32899389.

Alghounaim M, Almazeedi S, Al Youha S, Papenburg J, Alowaish O, AbdulHussain G, Al-Shemali R, Albuloushi A, Alzabin S, Al-Wogayan K, Al-Mutawa Y, Al-Sabah S. Low-Cost Polyester-Tipped 3-Dimensionally-Printed Nasopharyngeal Swab for the Diagnosis of Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2). J Clin Microbiol. 2020 Aug 12:JCM.01668-20. doi: 10.1128/JCM.01668-20.Epub ahead of print. PMID: 32817232.

Hasan A, Aldhahi W. Soluble Suppression of Tumorigenicity 2 is Directly Correlated with Glycated Hemoglobin in Individuals with an Average glycemia in the Normal/Prediabetes Range. Diabetes Metab Syndr Obes. 2020 Aug3;13:2711-2718. doi: 10.2147/DMSO.S251135. PMID: 32801817; PMCID: PMC7413703.

Alterki A, Joseph S, Thanaraj TA, Al-Khairi I, Cherian P, Channanath A, Sriraman D, Ebrahim MAK, Ibrahim A, Tiss A, Al-Mulla F, Rahman AMA, Abubaker J, Abu-Farha M. Targeted Metabolomics Analysis on Obstructive Sleep Apnea Patients after Multilevel Sleep Surgery. Metabolites. 2020 Sep 1;10(9):E358. doi:10.3390/metabo10090358. PMID: 32882816.

Mohammad A, Marafie SK, Alshawaf E, Abu-Farha M, Abubaker J, Al-Mulla F. Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2. Life Sci. 2020 Aug 5;259:118219. doi: 10.1016/j.lfs.2020.118219. Epub ahead of print. PMID: 32768580; PMCID: PMC7405906.

Al-Kandari H, Al-Abdulrazzaq D, Al-Jaser F, Al-Mulla F, Davidsson L. Rabson-Mendenhall Syndrome in a brother-sister pair in Kuwait: Diagnosis and 5 year follow up. Prim Care Diabetes. 2020 Aug 22:S1751-9918(20)30234-5. doi:10.1016/j.pcd.2020.07.012. Epub ahead of print. PMID: 32843252.

Al Shawaf E, Al-Ozairi E, Al-Asfar F, Mohammad A, Al-Beloushi S, Devarajan S, Al-Mulla F, Abubaker J, Arefanian H. Atherogenic Index of Plasma (AIP) a Tool to Assess Changes in Cardiovascular Disease Risk Post Laparoscopic Sleeve Gastrectomy. J Diabetes Res. 2020 Aug 1;2020:2091341. doi: 10.1155/2020/2091341.PMID: 32832558; PMCID: PMC7422485.

Al-Rashed F, Sindhu S, Arefanian H, Al Madhoun A, Kochumon S, Thomas R, Al-Kandari S, Alghaith A, Jacob T, Al-Mulla F, Ahmad R. Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway. Cells. 2020 Aug 12;9(8):E1892. doi: 10.3390/cells9081892. PMID: 32806763; PMCID: PMC7463685.

Abdel-Halim SM, Al Madhoun A, Nizam R, Melhem M, Cherian P, Al-Khairi I, Haddad D, Abu-Farha M, Abubaker J, Bitar MS, Al-Mulla F. Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study. Biology (Basel). 2020 Aug 24;9(9):E244.doi: 10.3390/biology9090244. PMID: 32847122.

AlSahow A, AlHelal B, Alyousef A, AlQallaf A, Marzouq A, Nawar H, Fanous G, Abdelaty M, Bahbahani Y, AlRajab H, AlTerkait A, Ali H. Renal Data from the Arab World Dialysis in Kuwait: 2013-2019. Saudi J Kidney Dis Transpl. 2020 Jul- Aug;31(4):826-830. doi: 10.4103/1319-2442.292317. PMID: 32801244.