Research Highlights

The Dasman Diabetes Biobank plays a pivotal role within the Dasman Diabetes Institute, serving as a central repository for numerous projects and initiatives. Its significance lies in its vast collect

Diabetes is a chronic disease that requires continuous engagement with healthcare services. To establish a comprehensive profile of individuals with diabetes and monitor their clinical outcomes, incl

The Glucagon receptor, GCGR, is a membranous receptor that plays an essential role in regulating glycemia. The main action of glucagon is to stimulate hepatic glucose production by increasing glycoge

The Biochemistry & Molecular Biology Department at DDI published an article that investigated the effects of increased toxicity caused by palmitic acid (PA) on insulin regulation. PA, a type of f

This study was a collaboration between Sorbonne Université and the Public Hospitals of Paris (Assistance Publique – Hôpitaux de Paris, AP-HP). It investigated the characteristics of immune cells in h

There is currently a global effort to apply large-scale genomic science and associated technologies to further the understanding of disease pathogenesis in diverse populations. These efforts focus on

Number and Impact factor of DDI’s published articles from 2016 until 2021. Here we highlight insightful published work in the department of Genetics and Bioinformatics: MMP9 is a molecule i

Kuwait is amongst top-ranking nations afflicted badly by obesity epidemic and its wide-scale complications such as increased blood pressure, heart disease, stroke, digestive problems, certain cancers

Prof. Fahd Almulla and his colleagues investigate what makes some cases of COVID-19 more severe. A striking feature of COVID-19 has been the variability in outcome, which ranges from silent infect

The autonomic nervous system is a control system that governs body activities such as digestion, respiratory rate, pupillary response, and heart rate in a mostly unconscious manner. This system i

Do you inherit your obesity from your mom? Maternally inherited mitochondrial DNA (mtDNA) is used to trace the kinship through the female line, it accumulates mutations over several generations. C

Number, Impact factor, and citations of DDI’s published articles have increased significantly during 2020 as compared to previous years. Here we highlight some of the published work in the dep

The rate of infection and mortality of SARS-CoV-2 varies based on the geographical spread of the virus as a consequence of several factors such as isolation, quarantine, differences in the genetic ma

DDI finds potentially critical biomarker of metabolic inflammation in obesity and diabetes Obesity, an important risk factor in the development of diabetes, is often associated with chronic infl

Why is the prevalence of obesity and metabolic disorders so high in the Middle East? Are diet and lifestyle choices the sole culprits? A new study1 conducted at Dasman Diabetes Institute may have fou

Immunometabolism has emerged recently as a very exciting field of research in immunology that investigates the interplay between immunological and metabolic processes. Interest in this field is gaini

BY DR. ALPHONSE T. THANGAVEL By performing an epidemiology study using cross-sectional data from Kuwait Health Network, we demonstrated recently that the association of higher body mass index (B

Prashantha Hebbar@, Mohamed Abu-Farha@, Anwar Mohammad, Fadi Alkayal, Motasem Melhem, Jehad Abubaker, Fahd Al-Mulla, Thangavel Alphonse Thanaraj* As an application of the SNP genotyping pipeline t

Mohamed Abu-Farha, Preethi Cherian, Irina Al-Khairi, Rasheeba Nizam, Abdullah Alkandari, Hossein Arefanian, Jaakko Tuomilehto, Fahd Al-Mulla & Jehad Abubaker Lipid metabolism is an important f

A typical human genome comprises around 3 billion letters (nucleotide bases); however, only a tiny fraction (~1%) of the bases constitute DNA regions that code for proteins. Genetic variability in su