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FATEMA AL-RASHED, PH.D, Post-doc Researcher Immunology & Microbiology Department

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Fatema Al-Rashed, Ph.D. is a post-doc researcher at the Immunology & Microbiology Department of Dasman Diabetes Institute in Kuwait, since 2016. From 2012 to 2015, she worked as a researcher at F

Immunometabolism – A Promising Route For Drug Development

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Immunometabolism has emerged recently as a very exciting field of research in immunology that investigates the interplay between immunological and metabolic processes. Interest in this field is gaini

In-situ Protein Detection “the Power Of In-cell Western Blotting”

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Western blot is a powerful technique originated in the laboratory of Harry Towbin at the Friedrich Miescher Institute in Basel, Switzerland in 1979. This sensitive immunological method identifies pro

The animal facility hosts new batches of Spague-Dawley rats and C57 mice

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1. The animal facility hosts new batches of Spague-Dawley rats and C57 mice. Scientists are welcome to utilize these animals for their existing and upcoming projects. 2. The protocol for the geno

Dr. Ashraf Al Madhoun

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Senior Scientist / Head of Department Animal and Imaging Core Facilities In 1990, Dr. Ashraf Al Madhoun graduated from Kuwait University and pursued his post graduate studies in Medicinal Pla

Spratt-dawley Rat Models For Diet-induced Obesity Leading To Hypertension And Diabetes.

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BY DR. ALPHONSE T. THANGAVEL By performing an epidemiology study using cross-sectional data from Kuwait Health Network, we demonstrated recently that the association of higher body mass index (B

Zebrafish As A Model For Obesity And Diabetes

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Obesity and diabetes are very common in Kuwait. The connection between the two diseases is so strong that they are often combined and referred to as ‘diabesity’. Both are complex diseases and are cau

Meet The Scientists Behind DDI’s Research – Special Services Facility

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MOTASEM MELHEM, Acting Manager of the OMICS Core Motasem is Senior Research Assistant. he has experience in wide range of genomics techniques such as DNA sequencing and RT-PCR, and quantitati

FTO SNP RS1421085 Increases Body Weight, Soft Lean Mass And Total Body Water Via Interaction With Ghrelin And Apolipoproteins.

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Prashantha Hebbar@, Mohamed Abu-Farha@, Anwar Mohammad, Fadi Alkayal, Motasem Melhem, Jehad Abubaker, Fahd Al-Mulla, Thangavel Alphonse Thanaraj* As an application of the SNP genotyping pipeline t

SNP Genotyping Pipeline: A Discovery And Innovation Pipeline

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DDI is a pioneering center in genetic research regionally and internationally. Alongside whole genome and whole exome sequencing, an inexpensive technology that investigates genetic variation within

Epigenetics Applications In Type 2 Diabetes: Rna Methylation Can Regulate Human SS-cell Biology And Insulin Secretion

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The regulation of islet cell biology is critical for glucose homeostasis. Multiple studies demonstrated that m6A mediators (writers, erasers and readers) are expressed in human islets from control gr

Dr. Jehad Abubaker

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Senior Scientist & Head of Department Dr. Jehad obtained his M.Sc. degree from University of Maryland School of Medicine, Baltimore, MD, USA specializing in Medical Research and Technology In

MIR-181D Plays A Protective Role Against Obesity By Regulating The Activity Of Angptl

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Mohamed Abu-Farha, Preethi Cherian, Irina Al-Khairi, Rasheeba Nizam, Abdullah Alkandari, Hossein Arefanian, Jaakko Tuomilehto, Fahd Al-Mulla & Jehad Abubaker Lipid metabolism is an important f

Epigenetics And Epitranscriptomics

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While Genetics, the study of gene expression, DNA sequencing and genetic variations, is important and has advanced our understanding of many diseases, the last two decades witnessed a renewal of inte

How Large Is The Repertoire Of T2DM Susceptibility Gene Loci?

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Genome-wide efforts to delineate the gene loci that are susceptible to type 2 diabetes began to take shape around the year 2000. The study cohorts largely represented people of European descent. Few

Meet the scientists behind DDI’s research

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MR. ARSHAD M CHANNANATH Arshad Mohammad Channanath has a master’s degree in bioinformatics and an advanced diploma in software engineering. His expertise includes analyzing and interpreting large

Genetic Variability In Protein-coding Regions Of The Human Genomes From Kuwait

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A typical human genome comprises around 3 billion letters (nucleotide bases); however, only a tiny fraction (~1%) of the bases constitute DNA regions that code for proteins. Genetic variability in su

Research at the department is aided by two components

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Research at the department is aided by two components – one with bioinformatics capabilities and the other with experimental genetics expertise. The core capabilities of the Bioinformatics component

Development And Implementation Of A National Diabetes Registry – Population Health Research

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Based on the experience with the ongoing pediatric diabetes registry, Kuwait will move ahead to develop and implement a comprehensive national registry including T1D, T2D and other forms of diabetes

History Of The Pediatric Diabetes Registry In Kuwait – Population Health Research

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In many countries, diabetes registries are in place to collect information on patients with diabetes to provide information for healthcare planning and monitoring of trends. In Kuwait, a registry was

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