New Model Sheds Light on the Link Between Fasting Blood Sugar and COVID-19 Morbidity
A new study linking fasting blood glucose in COVID-19 patients to coronavirus severity and the risk of being admitted to the intensive care unit offers fresh insights using a new statistical modeling
Researchers at Dasman Diabetes Institute Participate in Research Published in Nature Journal
A study by the NCD Risk Factor Collaboration, a group of health scientists around the world that publish global studies on obesity, diabetes, cholesterol, and blood pressure, was published in the jou
Exploring the Link Between Genes, Diabetes and COVID-19 Outcomes
Prof. Fahd Almulla and his colleagues investigate what makes some cases of COVID-19 more severe. A striking feature of COVID-19 has been the variability in outcome, which ranges from silent infect
Elevated resting heart as a predictor of cardiovascular risk in Healthy Obese individuals
The autonomic nervous system is a control system that governs body activities such as digestion, respiratory rate, pupillary response, and heart rate in a mostly unconscious manner. This system i
COVID19: N720D AN ACE2 VARIANT WITH HIGHER AFFINITY TO TMPRSS2
The rate of infection and mortality of SARS-CoV-2 varies based on the geographical spread of the virus as a consequence of several factors such as isolation, quarantine, differences in the genetic ma
Markers for Inflammation in Obesity and Diabetes
DDI finds potentially critical biomarker of metabolic inflammation in obesity and diabetes Obesity, an important risk factor in the development of diabetes, is often associated with chronic infl
COVID-19: DDI Find Possible Link Between Genetics and Disease Severity
Naturally occurring genetic variations in human populations may be the key to the differences in susceptibility to COVID-19 and the severity of its symptoms around the world. ACE2 and FURIN are im
Metabolic disorders In kuwait – are our Ancestral genes to Blame?
Why is the prevalence of obesity and metabolic disorders so high in the Middle East? Are diet and lifestyle choices the sole culprits? A new study1 conducted at Dasman Diabetes Institute may have fou
Immunometabolism – A Promising Route For Drug Development
Immunometabolism has emerged recently as a very exciting field of research in immunology that investigates the interplay between immunological and metabolic processes. Interest in this field is gaini
Spratt-dawley Rat Models For Diet-induced Obesity Leading To Hypertension And Diabetes.
BY DR. ALPHONSE T. THANGAVEL By performing an epidemiology study using cross-sectional data from Kuwait Health Network, we demonstrated recently that the association of higher body mass index (B
FTO SNP RS1421085 Increases Body Weight, Soft Lean Mass And Total Body Water Via Interaction With Ghrelin And Apolipoproteins.
Prashantha Hebbar@, Mohamed Abu-Farha@, Anwar Mohammad, Fadi Alkayal, Motasem Melhem, Jehad Abubaker, Fahd Al-Mulla, Thangavel Alphonse Thanaraj* As an application of the SNP genotyping pipeline t
MIR-181D Plays A Protective Role Against Obesity By Regulating The Activity Of Angptl
Mohamed Abu-Farha, Preethi Cherian, Irina Al-Khairi, Rasheeba Nizam, Abdullah Alkandari, Hossein Arefanian, Jaakko Tuomilehto, Fahd Al-Mulla & Jehad Abubaker Lipid metabolism is an important f
Genetic Variability In Protein-coding Regions Of The Human Genomes From Kuwait
A typical human genome comprises around 3 billion letters (nucleotide bases); however, only a tiny fraction (~1%) of the bases constitute DNA regions that code for proteins. Genetic variability in su
Research at the department is aided by two components
Research at the department is aided by two components – one with bioinformatics capabilities and the other with experimental genetics expertise. The core capabilities of the Bioinformatics component
Irf3 Is A Key Regulator Of Metabolic Inflammation, Insulin Resistance And Disruption Of Glucose Homeostasis
Obesity/overnutrition is associated with a state of chronic low-grade inflammation and its downstream metabolic effects greatly increase the risk of developing metabolic syndrome including Type 2 Dia
Fat Tissue And Metabolic Inflammation
Chronic low-grade inflammation is linked with obesity and has been shown to lead to insulin resistance and the development of type 2 diabetes. Inflammation is a vital process in our bodies, and part
Betatrophin: A Novel Biomarker For Obstructive Sleep Apnea And Dyslipidemia
Obstructive sleep apnea (OSA) is a well-known public health problem, with high prevalence and numerous complications, such as excessive daytime sleepiness and lack of focus, which impact the daily ac