Just one night of poor sleep could have these surprising health effects

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Researchers at the Dasman Diabetes Institute in Dasman, Kuwait, aimed to investigate how sleep quality impacts systemic inflammation and immune response in 237 participants.

After tracking the participants’ dietary intake, physical activity and sleep patterns, the researchers found that obese individuals had “significantly lower sleep quality and higher chronic low-grade inflammation,” according to a press release.

Sleep disruption also contributed to inflammation, regardless of obesity status. The experiment uncovered that just one night of sleep deprivation resulted in a disruption in immune cells, or monocytes, in these participants, similar to what was observed in obese participants.

The researchers concluded that this study “highlights the importance of sleep quality in regulating immune responses and inflammation in obesity, suggesting that improving sleep quality could reduce inflammation and improve health outcomes.”

For the publication:

Fatema Al-Rashed, Halemah Alsaeed, Nadeem Akhter, Haya Alabduljader, Fahd Al-Mulla, Rasheed Ahmad, Impact of sleep deprivation on monocyte subclasses and function, The Journal of Immunology, 2025;, vkae016, https://doi.org/10.1093/jimmun/vkae016

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